Endocrine Abstracts

Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary condition that most often manifests with primary hyperparathyroidism followed by other syndromes, but there are other variations in the clinical presentation, which can increase the risk of medical error and worsen prognosis. A 32-year-old woman presents with complaints of low glucose levels, hunger, weakness, sleep disturbances, which are stopped by taking sweets. At the age of 16, a pituitary macroadenoma, prola...

Osteoporosis is a systemic skeletal disease characterized by a decrease in bone strength and an increased risk of fractures. In the structure of osteoporosis, secondary osteoporosis is 5% in women and 20% in men. Clinicians need to exclude the secondary nature of osteoporosis, since under the ’mask’ of mineral metabolism disorders, more rare and dangerous diseases can arise. A 65-years-old women presents with complaints of three low-traumatic fractures in the last ye...

Thyroid orbitopathy (TO) is an autoimmune inflammatory disease of retroocular tissues. Mostly, TO is associated with Graves’ hyperthyroidism. The development of TO is accompanied by pathological changes in the soft tissues of the orbit with damage to the optic nerve and cornea, the accessory apparatus of the eye. Despite the presence of specific symptoms, the diagnosis of TO causes problems for doctors. A 61-year-old man complained of discomfort in the eyes, double vision...

Thyrotoxicosis (T) develops as a result of persistent excess of thyroid hormones (TH). There are two groups of diseases that are fundamentally different in pathogenesis. The first group includes those in which the production of TH increases. Diseases of the second group are accompanied by T caused by destruction of the thyroid gland tissue. Therapeutic approaches for different types of T are different, therefore, a careful differential diagnosis of T is necessary, even if at f...